Without selecting/highlighting, you can cut or delete an entire line in visual studio 2012. Just place your cursor on that line and –
1. Press Ctrl + Shift + L to delete a line
2. Presss Ctrl + L to cut a line.
Note that you can customize shortcut keys as following –
Go to Tools -> options. Tab Environment -> subtab Keyboard.
Select Edit.LineDelete. Assign a shortcut. Thats it.